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A variety of carriers based on bioengineered probiotics, dendrimers, polymersomes, and nanocarriers (such as nanoparticles, nanocapsule, nanoliposome, and nanopolymer) have been explored to deliver cargos (such as small molecule drugs, peptides, miRNA, siRNA, and plasmid DNA) for the treatment of RA and autoimmune diseases 37,38,39,40,41,42,43,44,45

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The Pf SDHA subunit, homologous to yeast Sdh1, is essential during late gametocyte development—stages where PD is particularly active